EXPLORING COMPOUND PROMISCUITY PATTERNS AND MULTI-TARGET ACTIVITY SPACES

EXPLORING COMPOUND PROMISCUITY PATTERNS AND MULTI-TARGET ACTIVITY SPACES

Blog Article

Compound promiscuity is rationalized as the Hockey Protective - Elbow Pads - Youth specific interaction of a small molecule with multiple biological targets (as opposed to non-specific binding events) and represents the molecular basis of polypharmacology, an emerging theme in drug discovery and chemical biology.This concise review focuses on recent studies that have provided a detailed picture of the degree of promiscuity among different categories of small molecules.In addition, an exemplary computational approach is discussed that is designed to navigate Wrapping Paper multi-target activity spaces populated with various compounds.